NordicImagingLab (NIL) is a medical software company, dedicated to the development of state-of-the-art software solutions for functional imaging methods. Through collaboration with highly ranked research groups and clinical users, their expert team has developed nordicICE (nordic Image Control and Evaluation). NordicImagingLab is a subsidiary of NordicNeuroLab, a developer and supplier of high-quality hardware products for functional imaging.
nordicICE is an easy-to-use Windows-based program (Windows 2000 and XP) that can readily be used as an integrated part of the daily diagnostic routine in any hospital. At the same time, nordicICE provides flexibility for the research oriented user who wants to explore and take advantage of the magnitude of possibilities in the program. NIL makes the latest methods and algorithms available for all users of nordicICE, and will continue to do so as the new and exciting functional MRI techniques continue to develop.
As a module-based application, nordicICE offers the flexibility to meet a variety of demands from different users. Running on top of the nordicICE Basis Module, optional plug-in modules are currently available for perfusion, diffusion and BOLD fMRI analysis.
Perfusion weighted imaging (PWI): describing tissue perfusion (capillary blood flow) and blood volume with high spatial resolution. nordicICE Perfusion Module are a fast and user-friendly perfusion analysis using state-of-the-art methods.
With the nordicICE Perfusion Module you can create high-quality perfusion maps from dynamic contrast enhanced MR and CT images in seconds, ensuring maximum productivity without loss of quality.
The nordicICE Perfusion Module can be used to obtain qualitative as well as (semi-) quantitative perfusion maps based on the dynamic (first-pass) effect of a contrast agent (CA). The noricICE Perfusion Module assumes that the input data describes a well-defined and transient signal response following rapid administration of a contrast agent. Analysis can be performed using a variety of different techniques.
Out-put perfusion maps: Blood Volume (BV), Blood Flow (BF),Mean Transit Time (MTT) and Time to Peak (TTP) or Delay (SVD) nordicICE allows you to do a “one-button” perfusion analysis using pre-defined settings.
(Developed in Professor Leif Østergaards laboratory)
This module offers fully automatic perfusion analysis in an intuitive and simple graphical environment. The program has been developed in close collaboration with clinicians to ensure optimal ease-of-use, especially in acute settings. By bringing together recent advances in automatic input function search strategies and deconvolution techniques, this program offers very fast and robust perfusion analysis.
Furthermore, nordicICE has a unique feature for integrating perfusion maps with other imaging data. For example, the penumbra region in acute stroke patients can be visualized by simply dragging the perfusion results on to a diffusion image.
The nordicICE Diffusion Module allows you to easily and effectively generate diffusion maps from MR diffusion imaing studies. These diffusion maps can be generated based on diffusion gradients applied in 1,3,6 and more directions. With 6 or more diffusion directions, diffusion tensor images (DTIs) are generated, supporting many of the standard parametric output maps.
The Diffusion Module also includes the novel feature of reconstructing axonal tracts in the central nervous system. The technique commonly referred to "fiber tracking" extends the capabilities of DTI and allows for the non-invasive study of the three-dimensional architecture of white matter tracts.
The nordicICE DTI 3D viewer allows the user to have an intuitive 3D visualization of reconstructed tracts superimposed on any image volume.
Within the viewer the user can display fiber statistics such as FA, ADC, tensor eigenvalues etc. The parametric values that is shown corresponds to the selected output maps that were generated during the DTI analysis. The user may do an interactive selection of individual fiber bundles too.
nordicICE allows you to explore connectivity by defining multiple Volumes-of-Interest with logical attributes (AND/OR/NOT). In nordicICE it is easy to superimpose BOLD fMRI activation as 3D “blobs” in the 3D viewer. You may save snapshots/animations to various file formats or directly to PACS.
Together with NordicNeuroLab’s fMRI Hardware System for stimulus presentation and response collection, the nordicICE BOLD Module and nordicAktiva combine to form a complete and user-friendly solution for simplifying and standardizing the implementation of functional MRI in clinical environments.
The nordicICE BOLD Module is a fMRI data analysis software, including the basic pre-processing steps, voxel-based statistical analysis using the General Linear Model, and visualization of statistical parametric maps. Additionally, the nordicICE BOLD Module offers specific data processing algorithms for all standardized paradigms available with nordicAktiva.
The fully-integrated, in-house developed software and hardware components reduce the need for an expert team and allow a single clinician to conduct an entire fMRI assessment from stimulus presentation and image acquisition, to data analysis and the reporting of results.
nordicICE enables integration of advanced functional MRI data-processing functionality in the Sectra PACS system. nordicICE can access data directly from the Sectra PACS as well as from other data sources accessible from the PACS client workstation in a variety of standard image formats. MRI data processed in nordicICE can easily be imported back to the PACS as an integrated part of the patient study.
Product Catalog for Sectra PACS Clinical Applications
